Welcome to the Minnesota Supercomputing Institute

Providing advanced research computing infrastructure and expertise to the University of Minnesota research and scholarly community and beyond.


MSI offers a variety of hardware, software, and consulting services to meet any research need.


MSI provides training and support for users of all experience levels.


MSI advances computational research across a broad range of disciplines.

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Interested in using MSI, or not sure where to start? Learn more about what MSI can do to support your research.

Server maintenance

June 2024 Maintenance


As we have previously warned, the monthly maintenance period for June at MSI will be longer than usual, with some services and the Agate cluster not returning to service for 2-3 days.

MSI Researcher Receives Grant for Equine Pangenome and Pantranscriptome Graphs

Awards Genetics Veterinary Medicine

Dr Jonah Cullen, in the MSI research group of PI Molly McCue (professor, Veterinary Population Medicine; Associate Dean of Research, CVM), has recently received a $218,000 grant from the USDA National Institutes of Food and Agriculture to develop pangenome and pantranscriptome graphs for horses.

Extended June MSI Maintenance – June 5-7, 2024


SummaryMSI reserves the first Wednesdays each month for maintenance tasks on its various computing, storage, and infrastructure systems. The next maintenance period, however, will be extended for 1-2 extra days in order for more upgrades to be completed to make MSI a more reliable and more capable resource for U of M researchers. You will not be able to use the HPC clusters from 5 a.m.

MSI PI Carol Lange to be 2025-26 Endocrine Society President


MSI PI Carol Lange (professor, Medicine ; Masonic Cancer Center) has been elected by the Endocrine Society to be the group’s 2025-26 president.

Fixes to R Library Issues

Maintenance Update

Due to recent changes to the computing environment around the move to Rocky Linux 8, MSI has been having difficulty providing a stable set of R modules for use on our systems.

UMN Single Cell Symposium 2024

The field of single-cell genomics has progressed rapidly over the last 10 years and has changed the way we ask and answer biological questions.

Soil Nutrient Management and the Soil Microbiome

Diseases caused by plant pathogens reduce the global food crop by 40% annually.

Improving Support for Caregivers

More than 30 million Americans provide unpaid care for a loved one as a caregiver.

Computational Modeling to Determine Effects of Climate Change Mitigation

As the largest terrestrial carbon pool, global soils provide great opportunity for climate change mitigation by transforming atmospheric CO2 as soil organic carbon (SOC) stocks.

Improving Convex Optimization

Convex optimization is an indispensable modeling and computational tool for all science and engineering fields.

Improving Crops Using High-Throughput Phenotyping

Breeding climate-resilient crops and developing targeted management practices are imperative to strengthening global food security.

Genomics and the Progression of Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF) is a deadly, progressive fibrotic lung disease.