Welcome to the Minnesota Supercomputing Institute

Providing advanced research computing infrastructure and expertise to the University of Minnesota research and scholarly community and beyond.

MSI Services

MSI offers more than 125 million hours of free computing annually to University of Minnesota faculty and collaborators. Access is determined by the “fair share” algorithm in the SLURM system, favoring groups with lower recent computing usage. To ensure access, faculty can lease dedicated hardware on existing HPC systems. Additional services and prices are detailed, including generous storage allocations for research projects. Groups needing extra storage beyond justified limits have options. For inquiries about purchasing dedicated access, visit our Helpdesk.

MSI’s Mission

We offer advanced research computing infrastructure and expertise to the University of Minnesota’s research community, scholarly groups, and the State of Minnesota. Our goal is to advance research, accelerate progress, and promote innovation and discoveries through cutting-edge technologies, scientific computing, informatics, application development, and various services.

A New Therapy to Treat Duchenne Muscular Dystrophy

Several MSI PIs are on a team that recently published a novel treatment for Duchenne muscular dystrophy.

Improving Catalytic Processes

MSI PI Paul Dauenhauser and colleagues have developed a method to develop new and more effective catalysts.

MSI PI Jim Anderson Appears on Award-winning Food Show

MSI PI James Anderson was featured on Relish, the award-winning food program on TPT-TV.

October 2025 Maintenance

MSI will perform scheduled maintenance on Wednesday, October 1, 2025.

GenoFest 2025

GenoFest features presentations from leaders in the genomics field, updates on the latest sequencing and multi-omic platforms, tours, posters, exhibitor tables, and connections with fellow researchers.

WiADS 2025

The Women in AI & Data Science (WiADS) Conference 2025 is an opportunity for women, women-identifying, and non-binary professionals, academics, and students to share their research, projects, and stories.

Mapping Minds: Cultivating GeoCommunities at the University

Connect with colleagues creating sustainable, equitable, and resilient solutions rooted in place but designed for global impact.

10X Users Group Meeting

The 10X Genomics User Group Meeting is for those who want to learn about the latest single cell and spatial multiomic solutions and to see how these platforms help researchers push the boundaries of discovery

A New Computational Method for Improving Brain-Behavior Correlation Associations

Several MSI PIs, Research Computing staff members, and colleagues at other institutions have developed a computational method to identify motion-caused artifacts in structural and functional MRI.

Creating a National Medical Price Repository

Researchers partnered with MSI to gather data and create a National Medical Price Repository that could help answer questions about healthcare spending and competition.

The Ag-Response Model

Researchers are creating the Ag-Response Model, an integrated assessment model of crop production in Minnesota.

Machine Learning Methods to Determine Arctic Methane Emissions

MSI PIs are using machine learning methods to reduce uncertainty in measuring estimates of methane emissions from Arctic lakes.